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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5R1
All Species:
19.39
Human Site:
S124
Identified Species:
38.79
UniProt:
Q15078
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15078
NP_003876.1
307
34060
S124
S
Q
T
G
G
S
S
S
V
K
K
A
P
H
P
Chimpanzee
Pan troglodytes
XP_001158783
424
45536
S241
S
Q
T
G
G
S
S
S
V
K
K
A
P
H
P
Rhesus Macaque
Macaca mulatta
XP_001113074
307
34072
S124
S
Q
T
G
G
S
S
S
V
K
K
A
P
H
P
Dog
Lupus familis
XP_548274
307
34112
S124
S
Q
T
G
V
S
S
S
V
K
K
A
P
H
P
Cat
Felis silvestris
Mouse
Mus musculus
O35926
369
38896
P160
G
K
P
P
P
P
P
P
P
A
P
Q
A
A
P
Rat
Rattus norvegicus
P61810
307
34013
S124
S
Q
T
G
V
S
S
S
V
K
K
A
P
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510972
134
15408
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079141
293
32627
N117
K
Q
I
S
S
I
K
N
V
S
N
T
S
G
G
Zebra Danio
Brachydanio rerio
NP_001002515
310
34763
P124
A
S
S
V
K
K
A
P
L
S
N
S
N
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523535
472
53508
Q290
L
T
L
S
L
P
Q
Q
V
Q
A
S
S
I
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22695
356
39856
T132
P
R
P
S
D
T
T
T
I
I
P
N
Y
Y
S
Sea Urchin
Strong. purpuratus
XP_794538
375
41683
P139
D
S
V
A
I
L
T
P
Q
K
K
D
S
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
99.6
99
N.A.
48.5
98.3
N.A.
36.4
N.A.
66.1
79.6
N.A.
35.5
N.A.
35.1
42.1
Protein Similarity:
100
70
99.6
99.6
N.A.
57.9
99
N.A.
40.7
N.A.
79.8
88
N.A.
46.4
N.A.
50.5
57.3
P-Site Identity:
100
100
100
93.3
N.A.
6.6
93.3
N.A.
0
N.A.
13.3
0
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
93.3
N.A.
0
N.A.
20
33.3
N.A.
20
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
9
0
0
9
9
42
9
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
42
25
0
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
0
% H
% Ile:
0
0
9
0
9
9
0
0
9
9
0
0
0
9
0
% I
% Lys:
9
9
0
0
9
9
9
0
0
50
50
0
0
9
0
% K
% Leu:
9
0
9
0
9
9
0
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
17
9
9
0
0
% N
% Pro:
9
0
17
9
9
17
9
25
9
0
17
0
42
0
50
% P
% Gln:
0
50
0
0
0
0
9
9
9
9
0
9
0
0
9
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
42
17
9
25
9
42
42
42
0
17
0
17
25
0
9
% S
% Thr:
0
9
42
0
0
9
17
9
0
0
0
9
0
0
0
% T
% Val:
0
0
9
9
17
0
0
0
59
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _